Monday, 22 December 2014

Enzyme Responsive Surfaces and Control of Neural Stem Cell Differention: Zelzer Group Presentations

Hala and Anne attended and presented their work at the 4th Postgraduate Symposium on Nanotechnology on the 15th December. The one day meeting was sponsored by the RSC Materials Chemistry Division and hosted at the School of Chemistry, University of Birmingham.

Postgraduates and Post Docs from Universities across the UK came together to share their exciting research with each other on topics ranging from carbon nanotubes for intracellular sensing to nanoparticles for cancer therapies.

Hala presented a poster of her work on designing surfaces that control neural stem cell differentiation and Anne delivered a flash presentation on designing an enzyme responsive surface.

The honorary guest speakers Dr Matthew I. Gibson (University of Warwick), Dr David Adams (University of Liverpool) and Dr Adam Perriman (university of Bristol) offered their experience and practices in their stimulating plenary talks. Lunchtime and evening poster sessions enabled the early researchers to discuss their work with one another over a beer or two.

Friday, 19 December 2014

Fabio Simoes presents for The Zelzer Group at NMAET SSBII Joint Conference

Fabio Simoes gave a presentation titled 'Control of peptide surface density through the application of polymers with precise chemical composition' at the joint meeting of Nano-Molecular Analysis for Emerging Technologies VI (NMAET VI) and Surface Science of Biologically Improtant Interfaces 15 (SSBII 15).

Fabio’s talk showcased his work on developing novel materials that contain a well-defined number of biomolecules (peptides). These materials are essential to to understand and develop advanced sensors for biomedical applications as they improve quantitative measurements of the amount of small biomoleucles (peptides) on surfaces.

The meeting was hosted at NPL (The National Physical Laboratory) from the 25th - 27th November, comprising an excellent variety of presentations from internationally leading scientists in the area of biomolecular surface measurements.

Wednesday, 12 November 2014

Photos from the Lab

This photo was taken by Zelzer Group member Sunil Rajput. The stairwell is commonly used to pose for group photos but looks equally stunning with no one actually on it. Here is Sunny's description of the photo.

The Boots science building is home to the Laboratory of Biophysics and Surface Analysis and other research groups such as Targeted Therapeutics, Drug delivery and Tissue engineering. Boasting its excellent research equipment and facilities the building is also home to the Interface and Surface Analysis Centre (ISAC), a joint venture between the University of Nottingham and the National Physics Laboratory. The image shows the stairwell between the second and third floors and its beautiful design.


Tuesday, 4 November 2014

New Review Published

A review by Matt Piggott and Mischa Zelzer is now published in Chemistry Today.

The review describes recent advances in surface and interface analysis and highlights how these developments may impact on research and development in the pharmaceutical industry.

The paper also promotes the concept that collaborations between universities and industry, facilitated by service facilities such as ISAC, can provide the capabilities required to integrate state of the art analysis facilities in industrial R&D.

Thursday, 16 October 2014

Science Outreach : Zelzer Group at Firbeck Academy

Zelzer Group members (Michael, Sunny and Anne), alongside other members of the University of Nottingham organised and ran an outreach activity day (Science WOW day) at Firbeck Academy for children aged 4 to 11. In an attempt to interest the next generation of scientists (hopefully) a range of tasks were prepared to put it bluntly, WOW the students.

Sunny getting set up for an experiment

Anne helping a young student

Mike getting ready to instruct

Monday, 13 October 2014

New Project Student: Ruggero Foralosso

Ruggero Foralosso will perform his CDT training project with Mischa Zelzer and David Scurr on the analysis of buried interfaces using ToF-SIMS. Ruggero is part of the Centre for Doctoral Training in Advanced Therapeutics and Nanomedicines.

Tuesday, 7 October 2014

Heart Blog Feature : There and Back Again - A Chemist's Journey to Pharmacy

Mischa is featured on the Heart Blog, telling the tale of the twists and turns that led him through his undergraduate studies in Chemistry and up to his lectureship at the School of  Pharmacy.

The Heart Blog features scientists within the healthcare engineering and regenerative medicine fields. Career stories as well as descriptions of current research are two of the common featured themes.

Mischa's feature can be found here.

Friday, 3 October 2014

New PhD Student: Deniz Uğur

Deniz Uğur has started his PhD project on the investigation of the effect of protein interactions with nanoparticles designed to deliver cells for therapeutic applications. He is an international student and his PhD is funded by the Nanofar Erasmus Mundus Joint Doctorate in nanomedicine and pharmaceutical innovation. Deniz is jointly supervised by Mischa Zelzer at the University of Nottingham and Frank Boury and Claudia Montero-Menei at the University of Angers in France. He begun his studies in Angers and will later join the group in Nottingham.

Wednesday, 24 September 2014

New PhD Student: Anne Canning

Anne Canning has joined the group to conduct research on designing enyzme responsive cell-material interfaces.

She is a PhD student within the Centre for Doctoral Training in Regenerative Medicine funded by the EPSRC and the MRC. Her project is supervised by Mischa Zelzer, Jonathan Aylott and Lee Buttery.

Monday, 7 July 2014

New Group Member: Arianna Pasquazi

Arianna Pasquazi has joined the group as a project student to work on enzyme responsive peptide surfaces. Arianna is a 4th Year Undergraduate studying for a Masters Degree in Pharmacy at the University of Rome “Tor Vergata”.

Her work is funded by a scholarship from her University - Stage di 4 mesi presso la School of Pharmacy dell’Università di Nottingham.

Saturday, 28 June 2014

Group Day Out: Barbecue

It is that time of year! As expected for an English summer, it poured down heavily at the start but the clouds ebbed away and by the time the food was cooked, there was some beautiful sunshine and time for a group photo!

Monday, 16 June 2014

New Group Member: Chris Strong

Christopher Strong is a 2nd year undergraduate MPharm student at The University of Nottingham who has joined the group to work on a summer project with Maria Marlow and Mischa Zelzer. The project is supported by The University of Nottingham Faculty of Science Dean's Fund and aims to explore the self assembly of drug precursors on surfaces.

Tuesday, 10 June 2014

Science Communication: Artificial Snot!

In a bid to inspire the next generation of scientists, Mike and Mischa together with other researchers from The University of Nottingham took a trip to Riverside Primary School to present fun scientific experiments.

This included, much to the students delight, artificial snot! The components of the snot much like real life mucus were proteins (gelatin) and sugar (syrup). While making snot as an experiment was well received by the students, adding in some food colouring to create ogre or alien snot really brought out the squeals!

Regular outreach activities are organised by the School of Pharmacy at Nottingham University.

Sunday, 1 June 2014

Gordon Research Conference: Mischa Zelzer


Renaissance Tuscany - GRC
Mischa Zelzer will be one of the  discussion leaders attending the Biointerface Science- Gordon Research Seminar and Conference in Italy.

The broad focus of the conference this year is in engineered biomolecular interfaces with diverse yet inter-related areas such as synthetic cellular interfaces, smart biomaterials and bioimaging.

The conference will take place at Renaissance Tuscany Il Ciocco Resort in Lucca (Barga), Italy. 

Thursday, 27 February 2014

Book Chapter Published


A book chapter written by Mischa Zelzer and Rein Ulijn appeared in 'Smart Polymers and their Applications', edited by M. R. Aguilar and J. S. Román and published by Woodhead Publishing.

The chapter introduces various aspects of enzyme responsive materials, including their fabrication, properties and application.

Friday, 10 January 2014

Mischa Zelzer Wins UKSAF Vickerman Prize

At the UK Surface Analysis Forum (UKSAF) January Meeting, Group leader Mischa Zelzer was awarded the inaugural Vickerman Prize for 2013.

This award is presented to researchers whose work is anticipated to have a major impact in the field of surface analysis. It is intended as a recognition of high quality independent research at an early career stage

The award is named after John Vickerman, the founding Chairman of the SIMS Users Group, in recognition of his pioneering work in SIMS and his leading role in UK surface and interface science.

In his early career, Mischa Zelzer has made substantial contributions to the development and characterisation of surfaces based on biological building blocks to advance the study of biomaterial interfaces. He has developed low cost methods to monitor the different stages of solid phase peptide synthesis on a surface which are now applied routinely. He has further employed surface analytical tools (ToF-SIMS) to investigate the interaction of peptide surfaces with biological entities such as enzymes.

In this award Mischa's contribution to the future of surface and interfacial studies is acknowledged.