Sebastiaan and Mischa recently published a communication titled ‘Multivariate analysis of 3D ToF-SIMS images: method validation and
application to cultured neuronal networks’ in Analyst with Christopher
Parmenter, David Scurr and Noah Russell as their co-authors. They demonstrate
that by using a training set approach principal components analysis (PCA) can
be performed on large 3D ToF-SIMS images of neuronal cell cultures. The method
readily p
rovides access to sample component information and significantly
improves the images’ signal-to-noise ratio (SNR).